Role Information

Title: Senior Systems Engineer
Reports to: VP of Engineering
Location: Boston/Cambridge, MA

Position Overview

This role is a critical part of Portal’s mission to advance PRIME Nexus® toward commercialization. You will work cross‑functionally with engineering, quality, regulatory, manufacturing, and external partners to help scale a novel drug‑delivery platform that directly impacts patient experience and therapeutic success.

This is an opportunity to take ownership, solve complex problems, and contribute meaningfully at a pivotal stage of Portal’s growth.

The Senior Systems Engineer will support the SW, Electrical Engineering, and Mechanical Engineering teams with designing, building, documenting and testing software controlled electromechanical systems.

What You’ll Do

Your Impact

Work closely with software, electrical and mechanical engineers to design, build, document and test electronics systems for next generation electromechanical autoinjectors and related test setups
Evaluate component and system performance by developing, executing, and documenting verification and validation plans. Evaluate the feasibility of meeting external partner needs.
Collaborate with cross-functional engineering and manufacturing teams to meet product launch goals

Key Responsibilities

Partner cross‑functionally to translate requirements into practical, compliant solutions
Support MRD / PRD development, documentation and lifecycle management
Support Risk Management documentation (RMF workbook, dFMEAs, pFMEAs, uFMEA) development
Evaluate component and system performance by developing, executing, and documenting verification and validation plans
Reliability Engineering / test fixture / test plan development
Engage with internal and external stakeholders, including vendors and partners

What We’re Looking For

Required Qualifications

Experience with interdisciplinary engineering with a degree related to Mechanical, Electrical, or Software Engineering.
5+ years of experience in medical devices, biotech, pharma, or a regulated industry
Experience working within quality systems (e.g., ISO 13485, design controls)
Ability to work effectively in a fast paced, collaborative environment
Experience with soldering, test, measurement setup and basic lab equipment (oscilloscope, DMM, DAQ, etc.)
Experience with mechanical fabrication for prototypes: machining, and 3D printing
Proven analytical, reporting, and documentation skills
Familiarity with ECAD tools such as Altium for schematic capture and PCB layout
Familiarity with CAD tools such as Solidworks for mechanical design
Experience with microelectronics and embedded systems
Experience programming in Python, C and C++
Experience automating test setups and data acquisition.

Preferred Qualifications

Experience with drug-device combination products
Exposure to human factors engineering, usability, or patient centric design
Experience supporting products through development, validation, or commercialization
Strong communication skills and comfort working cross functionally

How to Apply

Please submit a resume (and cover letter if applicable) to careers@portalinstruments.com. Candidates will be contacted if their background aligns with Portal's needs.

Pay: $120,000.00 - $160,000.00 per year

Benefits:

401(k)
401(k) matching
Dental insurance
Employee assistance program
Employee discount
Flexible spending account
Health insurance
Health savings account
Life insurance
Paid time off
Parental leave
Retirement plan
Vision insurance

Application Question(s):

Will you now or in the future require employer sponsorship for a work visa?

Education:

Bachelor's (Preferred)

Experience:

medical device: 5 years (Required)

Location:

Cambridge, MA 02141 (Required)

Ability to Relocate:

Cambridge, MA 02141: Relocate before starting work (Required)

Work Location: In person

Portal Instruments

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Senior Systems Engineer