Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a Bioinformatics Associate, Oncology to join our growing bioinformatics team. The bioinformatics team is responsible for analysis and pipeline development for our Northstar oncology products. Our sample volume is growing extremely quickly. As a Bioinformatics Associate, you will be working with a team of talented bioinformaticians to scale up our analysis pipeline to analyze tens of thousands of samples. The Bioinformatics Associate role is a full-time onsite position in Menlo Park, CA and reports to the Sr. Manager of Bioinformatics, Oncology.

Responsibilities:

Perform analysis of clinical bioinformatics data while maintaining low turnaround time for data delivery
Maintain and develop sophisticated and robust next-generation sequencing analysis pipeline
Collaborate with other teams from CLIA lab, Software Engineering, Quality Assurance, and R&D to improve and scale our clinical workflows

Qualifications:

BS or MS in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related field
Very strong programming skills in Python
Comfortable working in UNIX command-line environments
Experience deploying code in HPC or cloud computing environments
Strong communication skills
Great attention to detail
Can work in the United States without immediate sponsorship (For applicants on student visas, post-graduation OPT is acceptable)

Nice-To-Haves:

2 years of research or industry experience in biotechnology
Experience with software development in industry and ideally in a regulated environment
Experience with Molecular biology lab techniques (DNA purification, PCR, electrophoresis) or next-generation sequencing library preparation
Experience leading cross-functional projects involving teams of diverse backgrounds

Benefits And Perks:

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Free UNITY Complete NIPT testing for employees & spouses
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Free daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $115,655per year, including a base pay range of $85,331- $96,050per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

BillionToOne

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Bioinformatics Associate, Oncology